Determination of trilostane by hplc

Author: jxsv

August undefined, 2024

WebGas chromatography (GC) and high-performance liquid chromatography (HPLC) coupled to different detectors, and in combination with different sample extraction methods, are most widely used for analysis of triazine herbicides in different environmental samples. Nowadays, many variations and modificati … WebJul 1, 2012 · Acceptance criteria for trilostane content were set at 90–105% LC, which is consistent with current United States Pharmacopoeia criteria for shelf life specification of a drug product. The 0 mg control batches were removed from further evaluation after determination of 0% trilostane content and were not included in the statistical analysis.

High-performance liquid chromatographic analysis of …

WebJun 1, 2002 · Abstract and Figures. An isocratic reversed-phase liquid chromatographic (HPLC) method is proposed for the practical and reliable determination of triclosan, an … WebTrilostane ((4α,5α,17β)-3,17-dihydroxy-4,5-epoxyandrost-2-ene-2-carbonitrile); >= 98% HPLC; Trilostane has been used to evaluate its capability to regulate the sex-dependent differences in the lipopolysaccharide (LPS)-induced inflammatory responses of astrocytes; Trilostane inhibits the production hide hunting

The bioavailability and metabolism of trilostane in normal …

WebJan 1, 2011 · A new method for analysis of benzene, toluene, and xylene (BTX) using High Performance Liquid Chromatography-UV detection (HPLC-UV) is described and compared to the gas chromatography (GC) method. WebIn view of the problems described in the Reference Example in relation to the degradation of Trilostane on a silica-based stationary phase, an improved HPLC system, described … WebJun 14, 1991 · A simple high-performance liquid chromatographic (HPLC) method for assaying trilostane, a synthetic steroid, and one of its metabolites, ketotrilostane, in small volumes of rat plasma has been developed. A single liquid-liquid extraction was used to … hide icons on ipad

High-performance liquid chromatographic analysis of …

Isocratic HPLC Method for the Determination of Sorbitol and …

WebIn reversed-phase HPLC, fatty acids are separated both by chain length and by degree of unsaturation. The first double bond reduces the effective chain length by a little less than 2 carbon units, so an 18:1 fatty acid elutes just after 16:0. A second and further double bonds have smaller effects on retention so an 18:3 fatty acid elutes just ... WebA high-performance liquid chromatographic (HPLC) method for the determination of triclosan and triclocarban in cosmetic products was developed. Triclosan and triclocarban quantities in 168 of cosmetics were investigated and statistical analyzed with this method. The optimal condition are as follows: An Agilent SB-C8 analytical column (250 × 4. ... hide icons on the desktopWebAug 15, 2024 · The determination of caffeine content in coffee products is routinely done by RPLC in commercial applications in order to guarantee purity and quality of ground … hide icons on home screen

"WebOct 17, 2016 · The method was validated and all the factors influencing the separation and analysis were checked experimentally. The method ensures the separation of the five above-mentioned compounds with good resolutions in a relatively short run time. Accordingly, the proposed HPLC method can be applied for in-process and finished … " - Determination of trilostane by hplc

Determination of trilostane by hplc

HPLC Method for Analysis of Trilostane SIELC Technologies

WebMay 7, 2012 · Figure 2 shows a typical chromatogram of a working sample solution obtained under the optimized HPLC conditions described in the preceding. The amino-bonded silica packing has been widely used for the separation of carbohydrates. When used in the current study, it provided the required separation of sorbitol and glycerol from each other and … WebBrown et al. 4 describe an HPLC method for the determination of Trilostane and its 17-keto analogue using a silica-based Partisil column and a silica-based Phenyl/Corasil …

Did you know?

WebDec 9, 2015 · Box-Behnken design was applied to optimize high performance liquid chromatography (HPLC) conditions for the simultaneous determination of potassium sorbate, sodium benzoate, carmoisine, allura red, ponceau 4R, and caffeine in commercial soft drinks. The experimental variables chosen were pH (6.0–7.0), flow rate (1.0–1.4 … WebJan 1, 1984 · For quantitative analysis and for monitoring separations the mobile phase consisted of methanol--O.1 M formic acid (1:1) at a flow-rate of 2 ml/min. Both column …

WebA trilostane assay was developed for analysis. Trilostane (Vetoryl) capsules were used as clinical controls. Forty-four medication packets containing trilostane (Vetoryl), prepared … WebJun 14, 1991 · The aim of the present study was therefore to develop a sensitive and specific HPLC assay method for the determination of plasma levels of trilostane and …

WebTrilostane ((4α,5α,17β)-3,17-dihydroxy-4,5-epoxyandrost-2-ene-2-carbonitrile); >= 98% HPLC; Trilostane has been used to evaluate its capability to regulate the sex-dependent differences in the lipopolysaccharide (LPS)-induced inflammatory responses of astrocytes; Trilostane inhibits the production WebThus, plasma analysis is required to support in vivo studies in rats designed to maximise absorption. Two high-performance liquid chromatographic (HPLC) assays for trilostane …

WebFeb 27, 2015 · A high-performance liquid chromatography–fluorescence detection (HPLC-FLD) method was developed and validated for choline quantification in foods. Samples were extracted by homogenizing in chloroform/methanol/water and hydrolyzing in HCl-acetonitrile. Choline was derivatized using 1-naphthyl isocyanate and quantified by HPLC …

WebHigh pressure liquid chromatographic (HPLC) analysis of plasma taken over 8 h from ten normal male subjects medicated with 120 mg of trilostane revealed that the drug is rapidly metabolised into at least one metabolite, 17-keto trilostane. Both compounds were detected in the blood stream at concentr … hide icons on macbook proWebA high-performance liquid chromatographic (HPLC) method for the determination of triclosan and triclocarban in cosmetic products was developed. Triclosan and … how exchange rates change hide inactive driver optionWebThe Newcrom columns are a family of reverse phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups … how exchange transaction charges calculatedWebJul 30, 2024 · Analytical method for the quantitative determination of EDTA in Cosmetics has been developed and validated by high-performance liquid chromatography (HPLC) with UV detection at wavelength 280 nm. how exchange rate affect balance of paymentsWebJun 1, 1991 · A simple high-performance liquid chromatographic (HPLC) method for assaying trilostane, a synthetic steroid, and one of its metabolites, ketotrilostane, in small volumes of rat plasma has been developed. A single liquid-liquid extraction was used to isolate the two compounds from acidified plasma prior to the quantitative analysis. hide image on mobile cssWebApr 15, 2024 · The objective of this work was to develop and validate a rapid high performance liquid chromatography (HPLC) method for the quantitative analysis of fluorouracil (5-FU) in polymeric nanoparticles. ... how exchange works